https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47391 Wed 13 Mar 2024 08:10:34 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19042 Sat 24 Mar 2018 08:05:18 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44813 Mon 24 Oct 2022 09:38:43 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:30705 Fri 17 Nov 2017 10:12:10 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45637 P = 0.044), but this did not remain significant on multivariable analysis. PORT was not associated with differences in DSS or OS. The surgical salvage rate was similar in the PORT and surgery-only groups (41% vs 47%; P = 0.972). Perineural invasion was found to be an independent predictor of inferior DSS (hazard ratio (HR) 2.19), DFS (HR 1.89), and OS (HR 1.97). Significantly worse outcomes were observed for patients with ≥4 concurrent IRFs. The application of PORT was associated with lower rates of recurrence, but the benefit was less apparent on mortality. Patients with perineural invasion and multiple concurrent IRFs were found to be at greatest risk, representing a subset of intermediate-risk OSCC patients who may benefit from PORT.]]> Fri 04 Nov 2022 14:45:07 AEDT ]]>